I like to play a 4-3-3 /4-4-2 formation with an anchor man, midfielder as a go-between and a hidden Second Striker in the AMC role. My Wing forwards turn out as right and left midfielders in effect. It's akin to Barca's formation but with some very good tweaks.
GK: VDS
DF: Gary Neville, Vidic, Rio, Emanuelson
DMC: Cesc Fabregas
CM: Scholes
AMC: Rooney
LWF: Nani
RWF: C. Ronaldo
CF: Eto'o
Subs:
GK: Cech, Akinfeev
DF: Sergio Ramos, Kompany, Pique, Clichy, Kruger, Micah Richards
MF: Hargreaves, Kirk, Anderson, Fletcher, D. Gallagher (yeah it's me...)
FW: Giggs, Adu, Martin, Higuain
CF: Tevez, F. Campbell, Soldado