Best Player to use is Messi. I've somehow mastered playing him on the right flank. I recently played in league mode and he scored 42 goals (in 30) playing on the right flank and that's considering all the blue and grey arrows going around. I can't imagine what he'd be link in master league where there's development.
Best Player or should I say worst player to play against when the COM is using him...
The one and only ADRIANO!!!!
I have tried just about every defender and no one can stop him... So far my best chance of defending him is Toure because he has excessive pace so even when he gets beaten he can chase him down. Close by is Shevchenko... Don't know why he is so overrated.
That being said my best eleven (default stats)...
Toldo
Zanetti---Toure---Gallas---Carr
Rosicky--Vieira--Veron
Messi------------------J.S. Park
Ibrahimovic
And if I were to compile a list of my toughest opponents..
1.Given - Inhuman reflexes (can be irritating at times)
2.Maicon - Anyone that plays for Inter is overrated
3.Riise
4.Puyol
5.Materrazi
6.Vieira
7.Maniche
8.Dejan Stankovic - officially the worst player in PES 2008 after Adriano
9.Crespo
10.Adriano
11. Shevchenko
It's mostly Inter.. I can't stand them..