Sasuki's tip isn't bad. I like two strikers who are quite different, as I like to mix up my game as much as possible.
On PES4, I had a few unbelievable teams with the best strikers on the game, but without a doubt my most effective strike team was John Carew and Mateja Kezman. They're good players, but not world class, but on the pitch they were lethal. Carew won everything in the air and caused problems with his strength, while Kezman was a brilliant finisher and had good movement. They just worked a treat in tandem.
On this game, I'd probably go for something like Adriano and Rooney - I've never played them together, but Adriano's lethal and Rooney is quality in ML. Adriano's arguably the best all round out-and-out striker so he'd always be in. Tavano is fast and wicked after a couple of seasons, so that's not bad. Don't drop Ronaldinho though! Play him as an AM.