OK I see your going through what i've been through and i know how it feels.
Try this.
0) Back up your game saves.
1) Uninstall the game using the disk not the control panel. Insert the PES8 disk let it autorun then choose uninstall from the boot up menu.
2) After uninstall is complete - Go to the KONAMI folder under program files and delete it. In some cases the KONAMI folder may have been removed during the uninstall but double check anyway.
3) Click start button on task bar and go to run, then type regedit and click ok.
4) when regedit opens, Click on edit and then go to Find. A pop will apear type pro evolution soccer 2008 and click on - Find Next.
5) When the search has finnished (may take a while...) regedit will highlight your findings on the right side of the screen. Delete anything that is associated with Pro EVolution Soccer 2008.
WARNING! "make sure you DO NOT delete any files apart from those to do with PES2008"
6) Pressing the F3 button will take you to the next search to find anthing to do with PES2008, as the files are scattered around. Dont worry not much to delete.
7) Once your search is over regedit will alert you that there are no more files found for your search.
8) Now put your disk into the drive if not already in. Install the game but install it as administrator. You can only do this by browsing the disk from and not the autorun feature, as the autorun feature doesnt let you right click on the menu when it appears.
9) Go to the setup file when browsing disk and right click and choose "run as administrator"
10) Install the game and the official patch update. Again run that as administrator too.
11) Then install Deckz patch using AFS explorer, When you run AFS again run as administrator.
12) Apply the patch (refer to deckz patching instructions).
13) Go to C:\Program Files (x86)\KONAMI\Pro Evolution Soccer 2008
14) Right click on the PES2008 file and go to properties at bottom.
15) click on the compatibilty tab and tick the "run this program in compatibilty mode for" and select "Windows XP (service pack 2)".
16) on the same pop up go down to "Privilege Level" and tick "Run as Administrator".
17) Now cross your fingers and wish for the best try running the game....
The above is what I did and it worked a wonder.

I hope this works for you too.